Arrhythmias & electrophysiology

Quantitative investigation of acute lesions created by ethanol infusion into the vein of Marshall

Heart RhythmPublished Mechanistic study

Authors' conclusion

EIVOM provided significant therapeutic effects on the left atrial tissue perpetuating atrial fibrillation, which was demonstrated by a quantitative analysis.

Study context

Population
Patients undergoing AF ablation with ethanol infusion into the vein of Marshall
Comparison
Before vs after EIVOM; with vs without EIVOM
Outcome
Quantitative analysis of lesions created by EIVOM (voltage maps before and after EIVOM)
Follow-up
30 and 60 minutes after EIVOM

Main finding

As reported in the abstract

Voltage significantly reduced after EIVOM; significant differences in voltage reduction between control status and 30 and 60 min after EIVOM
P < .05
Average contact force for successful conduction block in Marshall vein area significantly lower with vs without EIVOM
P < .05
Total epicardial fat volume (CT) significantly decreased after EIVOM
P < .05
Complex fractionated atrial electrogram area significantly decreased after EIVOM
P < .05

Original publication

Quantitative investigation of acute lesions created by ethanol infusion into the vein of Marshall. Heart Rhythm. Published 2 July 2024. doi:10.1016/j.hrthm.2024.06.054

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