Aortic & peripheral vascular disease

Radiographic complicated and uncomplicated descending aortic dissections: aortic morphological differences by CT angiography and risk factor analysis

Eur Heart J Cardiovasc ImagingPublished Retrospective cohort study

Authors' conclusion

We identified significant morphological differences and predictors for adverse events in patients presenting complicated and uncomplicated descending dissections.

Study context

Population
Patients with acute descending aortic dissection, April 2009–July 2021
Participants
209 patients
Exposure
Complicated vs uncomplicated acute descending aortic dissection
  • Complicatedn = 74
  • Uncomplicatedn = 135reference
Outcome
Early aortic failure:
  • Reoperation
  • Diameter progression
  • Early mortality
Methodological detailsDetailed CTA measurements (slice thickness ≤ 3 mm) in multiplanar reconstruction
  • Detailed CTA measurements (slice thickness ≤ 3 mm) in multiplanar reconstruction

Main finding

As reported in the abstract

Morphological differences, complicated vs uncomplicated descending dissections

Complicated

14.0

interval as printed 12.0 mm; 27.0 mm · mm

P = 0.005

Dissection extended more frequently to aortic bifurcation in complicated
P = 0.044
Coeliac trunk originated less frequently from true lumen in complicated
P = 0.003
Superior mesenteric artery originated less frequently from true lumen in complicated
P = 0.007
Both iliac arteries originated less frequently from true lumen in complicated
P < 0.001

Observational data: associations, not effects.

Further findings

Risk factors for adverse aortic events

HR (95% CI)
Connective tissue disease8.0 (1.9–33.7)
Length of the aortic arch4.7 (1.5–15.1)
False lumen diameter > 19.38 mm3.389 (1.1–10.2)
Inferior mesenteric artery from false lumen4.2 (1.0–5.5)

Female sex

P = 1.00

Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.

Original publication

Radiographic complicated and uncomplicated descending aortic dissections: aortic morphological differences by CT angiography and risk factor analysis. Eur Heart J Cardiovasc Imaging. Published 25 January 2024. doi:10.1093/ehjci/jeae030

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