Arrhythmias & electrophysiology
Rate and nature of complications of conduction system pacing compared with right ventricular pacing: Results of a propensity score–matched analysis from a multicenter registry
Authors' conclusion
Globally, CSP was associated with a risk of complications similar to that of RVP. Considering HBP and LBBAP separately, HBP showed a significantly higher risk of complications than did both RVP and LBBAP whereas LBBAP showed a risk of complications similar to that of RVP.
Study context
- Population
- Consecutive patients undergoing pacemaker implantation
- Participants
- 1,029 patients · 201 matched pairs
- Exposure
- Conduction system pacing (CSP) vs right ventricular pacing (RVP)
- RVPn = 201reference
- His bundle pacing (HBP)n = 128
- Left bundle branch area pacing (LBBAP)n = 73
- Outcome
- Device-related complications
- Follow-up
- Mean 18 months
Methodological detailsmulticenter, propensity-score matched, registry
- Multicenter
- Propensity-score matched
- Registry
Main finding
As reported in the abstract
P = 0.240
Observational data: associations, not effects.
Further findings
| Outcome | CSP | RVP | HBP | LBBAP | P value | |
|---|---|---|---|---|---|---|
| Device-related complications by pacing modality (subgroup)HBP vs RVP | Not reported in the abstract | 3.5% | 8.6% | 1.3% | P = 0.047 | CSP: not reported in the abstract |
| Device-related complications by pacing modality (subgroup)HBP vs LBBAP | P = 0.034 | |||||
| Device-related complications by pacing modality (subgroup)LBBAP vs RVP | P = 0.358 |
- Device-related complications by pacing modality (subgroup) — Lead-related share of complications with HBP
- 63.6%
Original publication
Rate and nature of complications of conduction system pacing compared with right ventricular pacing: Results of a propensity score–matched analysis from a multicenter registry. Heart Rhythm. Published 10 March 2023. doi:10.
Summarised from the published abstract; every number is checked against it