Heart failure & cardiomyopathies

Rationale, design, and baseline characteristics of the virtual care to improve heart failure outcomes (VITAL-HF) trial

Am Heart JPublished Design and baseline characteristics report of the VITAL-HF randomised controlled trial

Study context

Population
Patients with HF with reduced ejection fraction (HFrEF) (LVEF ≤40%) with smartphone access and English proficiency
Participants
178 patients
Comparison
Remote digital guideline-directed medical therapy (GDMT) optimisation intervention vs usual care
Primary endpoint
Change from baseline in GDMT by HF Collaboratory Score (HFC; use and dose of prescribed GDMT)
Follow-up
6 months
Methodological detailsmulticentre
  • Multicentre

Primary result

As reported in the abstract

Baseline characteristics · enrolment
Age, median (Q1-Q3), years
66.4 (56.1-73.1)
Female
38.8%
Hypertension
71.3%
CAD
45.5%
AF/flutter
31.5%
T2DM
28.1%
HFC score, median (Q1-Q3)
5 (4-6)
Evidence-based beta blocker
84.8%
ARNI
48.9%
MRA
48.9%
SGLT2 inhibitor
47.2%

Original publication

Rationale, design, and baseline characteristics of the virtual care to improve heart failure outcomes (VITAL-HF) trial. Am Heart J. Published 3 June 2025. doi:10.1016/j.ahj.2025.06.001

Composed by AI from the published abstract and checked against it. How Briefs are made →

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