Acute cardiac care & resuscitation
Rationale and design of the ULYSS trial: A randomized multicenter evaluation of the efficacy of early Impella CP implantation in acute coronary syndrome complicated by cardiogenic shock
Study context
- Population
- Patients with AMI complicated by cardiogenic shock (AMICS) for whom emergent percutaneous coronary intervention (PCI) is intended
- Planned comparison
- Pre-PCI Impella CP plus standard medical therapy vs PCI and standard medical therapy
- Primary endpoint
- Composite of:
- Death
- Need to escalate to ECMO
- Long-term LV assist device
- Heart transplantation
- Follow-up
- 1 month
Methodological detailsdesign paper, prospective, open label, 2 parallel groups, multicentre, Secondary objectives: 1-year efficacy, safety and cost effectiveness
- Design paper
- Prospective
- Open label
- 2 parallel groups
- Multicentre
- Secondary objectives: 1-year efficacy, safety and cost effectiveness
No results yet. This paper sets out the design of a trial; its results are to come.
Original publication
Rationale and design of the ULYSS trial: A randomized multicenter evaluation of the efficacy of early Impella CP implantation in acute coronary syndrome complicated by cardiogenic shock. Am Heart J. Published 30 August 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →