Arrhythmias & electrophysiology

Real-world data of radiofrequency catheter ablation in paroxysmal atrial fibrillation: Short- and long-term clinical outcomes from the prospective multicenter REAL-AF Registry

Heart RhythmPublished Prospective multicentre registry study

Authors' conclusion

Refinement of RF CA to treat PAF using contemporary tools, standardized protocols, and electrophysiology laboratory workflows resulted in excellent short- and long-term clinical outcomes.

Study context

Population
Patients undergoing radiofrequency (RF) catheter ablation for paroxysmal AF, January 2018 to December 2022
Participants
2,470 patients · 42 institutions
Outcome
Freedom from all-atrial arrhythmia recurrence
Follow-up
12 months
Methodological details42 high-volume institutions
  • 42 high-volume institutions

Main finding

As reported in the abstract

Freedom from all-atrial arrhythmias at 1 year

81.6%

Of these, off antiarrhythmic drugs

89.7%

Observational data: associations, not effects.

Further findings

PVI vs PVI plus ablation approaches

No significant difference comparing PVI vs PVI plus ablation

Procedures without fluoroscopy

Procedures performed without fluoroscopy
71.5%

Procedural time

Average procedural time (± 41.7 minutes)
95.4 minutes

Total RF time

Average total RF time (±11.8 minutes)
22.1 minutes

Safety

Complication rate
1.9%

Original publication

Real-world data of radiofrequency catheter ablation in paroxysmal atrial fibrillation: Short- and long-term clinical outcomes from the prospective multicenter REAL-AF Registry. Heart Rhythm. Published 19 May 2024. doi:10.1016/j.hrthm.2024.04.090

Summarised from the published abstract; every number is checked against it

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