Arrhythmias & electrophysiology
Iodinated Adhesive Drapes for Repeat Cardiac Implantable Device Implantation: A Randomized Clinical Trial
Primary result · Pocket-swab culture positivityResult — go to the resultRelative risk reduction 0.50 95% CI 0.24–0.75Authors' conclusion
In this randomized clinical trial, the use of iodine-impregnated drapes during repeat CIED implantation resulted in reduction in swab culture positivity and 1-year CIED infection rates.
Study context
- Population
- Patients undergoing repeat procedures on the same cardiac implantable electronic device (CIED) pocket189 + 195 analysed
- Participants
- 418 patients
- Comparison
- Iodine-impregnated adhesive drape vs no drape
- Drapen = 210
- No-drapen = 208reference
- Primary endpoint
- End-of-procedure pocket-swab culture positivity
Methodological detailssingle-blinded, single-centre, 1:1 randomisation
- Single-blinded
- Single-centre
- 1:1 randomisation
Primary result
Pocket-swab culture positivity
Relative risk reduction
0.50
95% CI 0.24–0.75
P = 0.005
Events by treatment group
Drapevs No-drape
relative risk reduction 0.50 (95% CI 0.24–0.75); P = 0.005
As reported in the abstract
Further findings
| Outcome | OR (95% CI) | P value | |
|---|---|---|---|
| CIED infection by swab result (positive vs negative swabs)2 of 59 (3.4%) vs 2 of 325 (0.6%) | 5.67 (0.78–41.04) | P = 0.08 | |
| 0.050.21520Odds ratio (log scale) |
| Outcome | Drape | No-drape | P value |
|---|---|---|---|
| Adjudicated CIED infections | 0 events | 1.9% | P = 0.02 |
Original publication
Iodinated Adhesive Drapes for Repeat Cardiac Implantable Device Implantation: A Randomized Clinical Trial. JAMA Cardiol. Published 1 October 2025. doi:10.
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