Recovery of Biventricular Function After Catheter Intervention or Surgery for Neonatal Coarctation of the Aorta
Authors' conclusion
Initial treatment of isolated CoA by percutaneous transcatheter intervention or surgical repair results in recovery of biventricular systolic function, making transcatheter treatment particularly suitable as rescue therapy for neonates with critical CoA.
Study context
- Population
- Neonates with isolated critical coarctation of the aorta (CoA), 2012–2021
- Participants
- 26 neonates
- Exposure
- Transcatheter intervention vs surgical CoA repair
- Interventionaln = 10
- Surgicaln = 16reference
- Outcome
- Echocardiographic isthmus diameter and biventricular function
- Follow-up
- Baseline and hospital discharge
Methodological detailssingle-centre, consecutive neonates
- Single-centre
- Consecutive neonates
Main finding
As reported in the abstract
Full recovery of biventricular systolic function before discharge, incl. normalization of longitudinal, radial and circumferential left ventricular (LV) strain and longitudinal RV free wall strain
26
Observational data: associations, not effects.
Further findings
Isthmus diameter increase with therapy
Cardiogenic shock at admission
Pre-therapy LVEF <50%
| Outcome | Interventional | Surgical |
|---|---|---|
| Pre-therapy longitudinal strain | ||
| LV | −12.3% | −16.3% |
| RV | −13.8% | −16.1% |
Original publication
Recovery of Biventricular Function After Catheter Intervention or Surgery for Neonatal Coarctation of the Aorta. JACC Adv. Published 10 May 2023. doi:10.
Summarised from the published abstract; every number is checked against it