Valvular & structural heart disease
Redefining cardiac damage staging in aortic stenosis: the value of GLS and right ventricular-arterial coupling (RVAc)
Authors' conclusion
A model that includes LV-GLS, MR, and RVAc may help to improve prognostic stratification and contribute to better selection of patients undergoing TAVR.
Study context
- Population
- Patients with severe aortic stenosis (AS) undergoing transcatheter aortic valve replacement (TAVR), 2017–2021mean age 82.1 ± 5.9 years
- Participants
- 496 patients
- Exposure
- New cardiac damage staging vs previously published staging systems
- Outcome
- All-cause mortality
- Follow-up
- 1 year
Methodological detailssingle-centre, prospective registry
- Single-centre
- Prospective registry
Main finding
As reported in the abstract
1-year all-cause mortality: predictive performance of staging models
- New 4-stage classification (left ventricle global longitudinal strain (LV-GLS), mitral regurgitation (MR), RVAc): AUC
- 0.66 (95% CI 0.63-0.76)
- Predictive performance of new system superior to previously published systems
- P < 0.001
Observational data: associations, not effects.
Original publication
Redefining cardiac damage staging in aortic stenosis: the value of GLS and RVAc. Eur Heart J Cardiovasc Imaging. Published 14 June 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →