Valvular & structural heart disease
Prognostic Value of Right Atrial Function in Patients with Significant Tricuspid Regurgitation
Authors' conclusion
RAGLS is associated with all-cause mortality and hospitalization due to heart failure in patients with significant TR.
Study context
- Population
- Outpatients with moderate or severe tricuspid regurgitation (TR) due to left-sided heart diseases, without AF, undergoing transthoracic echocardiography June 2020–April 2023
- Participants
- 169 outpatients
- Exposure
- Low vs high RA global longitudinal strain (RAGLS)
- Outcome
- All-cause mortality or HF hospitalization
- Follow-up
- Median 13 months
Main finding
As reported in the abstract
Low RAGLS vs High RAGLSHazard ratio (95% CI)P value
Multivariate Cox, model including RV dysfunction
4.55(1.51–13.71)
P < 0.01Multivariate Cox, model including high RAVI
4.57(1.52–13.79)
P < 0.01- Higher event rates with low RAGLS (Kaplan-Meier, log-rank)
- P = 0.003
Observational data: associations, not effects.
Further findings
| Outcome | With events | Without events | P value |
|---|---|---|---|
| RAGLS in patients with vs without events | 13% (SD 10%) | 18% (SD 9%) | P = 0.02 |
Events by RA volume index (RAVI) (high ≥50 vs low <50 mL/m²)
- Higher event rates with high RAVI (log-rank)
- P < 0.001
Original publication
Prognostic Value of Right Atrial Function in Patients with Significant Tricuspid Regurgitation. ESC Heart Fail. Published 2 August 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →