Cardiometabolic & kidney

Redefining Cardiometabolic Disease: Expert Consensus on the CardioVascular–Kidney–Liver–Metabolic (CardioVascular-kidney-liver-metabolic (CVKLM)) Multiorgan Staging

Eur J Prev CardiolPublished Expert Consensus

Scope

As issued by the authors

The cardioVascular-kidney-liver-metabolic (CVKLM) framework is a multidimensional staging system in which cardiac, vascular, kidney, liver, and metabolic involvement are graded independently from absent to advanced; intended for clinical and research phenotyping and staging rather than as a validated global risk score.

Original publication

Redefining Cardiometabolic Disease: Expert Consensus on the CardioVascular–Kidney–Liver–Metabolic (CVKLM) Multiorgan Staging. Eur J Prev Cardiol. Published 27 October 2026. doi:10.1093/eurjpc/zwag563

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