Valvular & structural heart disease
Redo Surgical Aortic Valve Replacement After Prior Transcatheter Versus Surgical Aortic Valve Replacement
Authors' conclusion
The number of post-TAVR reoperations is increasing and represent a high-risk population. Yet even in isolated SAVR cases, SAVR after TAVR is independently associated with increased risk of mortality.
Study context
- Population
- Patients undergoing bioprosthetic surgical aortic valve replacement (SAVR) after transcatheter aortic valve replacement (TAVR) and/or SAVR, STS Database 2011–2021
- Participants
- 31,106 patients
- Exposure
- Redo SAVR after prior TAVR vs after prior SAVR
- TAVR-SAVRn = 1,126
- SAVR-TAVR-SAVRn = 674
- SAVR-SAVRn = 29,306reference
- Outcome
- Operative mortality
Methodological detailsregistry (STS Database), risk-adjusted (hierarchical logistic regression), propensity-score matched (isolated SAVR)
- Registry (STS Database)
- Risk-adjusted (hierarchical logistic regression)
- Propensity-score matched (isolated SAVR)
Main finding
As reported in the abstract
Odds ratio
1.53
P = 0.004
TAVR-SAVR
Odds ratio
1.02
P = 0.927
SAVR-TAVR-SAVR
Observational data: associations, not effects.
Further findings
| Outcome | Times higher | P value |
|---|---|---|
| Operative mortality, isolated SAVR (propensity-score matched)TAVR-SAVR vs SAVR-SAVR · propensity-score matched | 1.74 | P = 0.020 |
Yearly rates of redo SAVR
- TAVR-SAVR and SAVR-TAVR-SAVR increased over time; SAVR-SAVR stable
Original publication
Redo Surgical Aortic Valve Replacement After Prior Transcatheter Versus Surgical Aortic Valve Replacement. JACC Cardiovasc Interv. Published 24 April 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →