Relationships between neighborhood disadvantage and cardiovascular findings at autopsy in subjects with sudden death
Authors' conclusion
Neighborhood disadvantage did not associate with cause of death or coronary histopathology after adjustment for cardiovascular risk factors and race
Study context
- Population
- Sudden death cases in the State of Maryland, CVPath Sudden Death RegistryArea deprivation index (ADI) available
- Participants
- 1,464 cases
- Exposure
- Most disadvantaged neighborhoods vs less disadvantaged neighborhoods
- ADI ≥ 8n = 607
- ADI ≤ 7n = 857reference
- Outcome
- Causes of death and gross and histopathologic findings of the heart
Methodological detailsautopsy registry
- Autopsy registry
Main finding
As reported in the abstract
Cardiac cause of death, most vs less disadvantaged neighborhoods
61.8% vs 67.7%
P = 0.02
Plaque rupture, most vs less disadvantaged neighborhoods
18.8% vs 25.1%
P = 0.004
Observational data: associations, not effects.
Further findings
Plaque rupture
P = 0.004
Age at death
P = 0.02
- Plaque rupture: not significant after adjustment for traditional risk factors and race
Age at death
- ADI ≥ 8 more likely Black or women
Original publication
Relationships between neighborhood disadvantage and cardiovascular findings at autopsy in subjects with sudden death. Am Heart J. Published 11 November 2022. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →