Arrhythmias & electrophysiology
Repeat pulmonary vein isolation and anterior line ablation using a novel point-by-point pulsed-field ablation system
Authors' conclusion
This study demonstrated feasibility, acute efficacy, and safety of point-by-point PFA for repeat PVI and AL ablation.
Study context
- Population
- Consecutive patients undergoing repeat AF ablation (PV reisolation; Anterior line (AL) in anterior substrate or durable pulmonary vein isolation (PVI))67% persistent AF
- Participants
- 24 patients
- Outcome
- Feasibility, safety and lesion characteristics of point-by-point PFA
Methodological detailsconsecutive patients
- Consecutive patients
Main finding
As reported in the abstract
Successful reisolation of reconnected PVs
Reconnected pulmonary veins (PVs) successfully reisolated
27 of 27
100%
Observational data: associations, not effects.
Further findings
AL ablation (n = 19)
- Bidirectional block
- 16 (84%)
- Median ablation time, minutes
- 26 [21, 33]
- First-pass bidirectional block
- 13 (68%)
- Acute AL reconduction
- 8 of 19 (42%)
- Subsequent sustained AL block among those with reconduction
- 5 (63%)
Procedural times (median, minutes)
- Procedural time
- 100 [90, 109]
- Left atrial dwell time
- 83 [75, 98]
- Fluoroscopy time
- 10 [8, 13]
Ultra-high-density electroanatomic mapping
- Homogeneous but relatively large low-voltage areas in ablated regions
Safety
- No major or minor complications
Original publication
Repeat pulmonary vein isolation and anterior line ablation using a novel point-by-point pulsed-field ablation system. Heart Rhythm. Published 29 November 2023. doi:10.
Summarised from the published abstract; every number is checked against it