Pulmonary vascular disease & thromboembolism
Safety and Feasibility of On-the-Table Pharmacomechanical Lysis for Acute Intermediate-Risk Pulmonary Embolism: The RESCUE-II Study
Authors' conclusion
On-the-table PML using the Bashir catheter effectively reduced RV/LV ratio and PA obstruction. The procedure was safe, with no major bleeding complications, and offers a rapid, cost-effective treatment option for patients with acute IR-PE.
Study context
- Population
- Symptomatic patients with IR-PE (computed tomographic-derived RV/LV ratio ≥0.9)enrolled and successfully treated
- Participants
- 9 patients
- Outcome
- Change in RV/LV ratio (primary efficacy endpoint)
- Follow-up
- 48 hours
Main finding
As reported in the abstract
- Mean RV/LV ratio before
- 1.66 ± 0.56
- Mean RV/LV ratio at 48 hours
- 1.27 ± 0.41
- P
- P = 0.0001
Observational data: associations, not effects.
Further findings
Pulmonary artery obstruction (Refined Modified Miller index) · 48 hours
- Reduction
- 29.2%
Procedure time
- Median procedure time
- 39 ± 13.4 minutes
Safety
Major bleeding within 72 hours (primary safety endpoint)
- No major bleeding events
Minor access site hematoma
- Patients with minor access site hematoma, managed with manual compression
- One
Original publication
Safety and Feasibility of On-the-Table Pharmacomechanical Lysis for Acute Intermediate-Risk Pulmonary Embolism: The RESCUE-II Study. JACC Adv. Published 19 May 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →