Restoring microvascular circulation with diagnostic ultrasound and contrast agent: rationale and design of the REDUCE trial
Study context
- Population
- Patients presenting with STEMI undergoing primary PCIplanned sample size
- Participants
- 150 patients
- Planned comparison
- Sonothrombolysis vs sham echocardiography before and after primary percutaneous coronary intervention (pPCI)
- Primary endpoint
- Infarct size on Cardiac Magnetic Resonance (CMR)
- Follow-up
- Day 4±2
Methodological detailsdesign paper, prospective, multicentre, patient and outcome blinded, sham-controlled, Follow-up 6 months post pPCI for secondary endpoints
- Design paper
- Prospective
- Multicentre
- Patient and outcome blinded
- Sham-controlled
- Follow-up 6 months post pPCI for secondary endpoints
No results yet. This paper sets out the design of a trial; its results are to come.
Original publication
Restoring microvascular circulation with diagnostic ultrasound and contrast agent: rationale and design of the REDUCE trial. Am Heart J. Published 27 June 2024. doi:10. 1016/ j. ahj. 2024. 06. 008
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