Valvular & structural heart disease
Right ventricular ejection fraction assessed by computed tomography in patients undergoing transcatheter tricuspid valve repair
Main finding · Additional value beyond 2D echocardiographic RV function assessmentResult — go to the resultHazard ratio 2.99 95% CI 1.65–5.41Authors' conclusion
CT-RVEF is associated with the risk of the composite outcome after TTVR, and a reduced CT-RVEF might attenuate the prognostic benefit of TR reduction.
Study context
- Population
- Patients undergoing transcatheter tricuspid valve repair (TTVR), right ventricular ejection fraction (RVEF) by pre-procedural cardiac CT
- Participants
- 157 patients
- Exposure
- CT-RVEF <45% vs ≥45%
- CT-RVEF <45%n = 58
- Outcome
- Composite of:
- All-cause mortality
- HF hospitalisation
- Follow-up
- 1 year after TTVR
Main finding
As reported in the abstract
Additional value beyond 2D echocardiographic RV function assessment
Hazard ratio
2.99
95% CI 1.65–5.41
P = 0.001
CT-RVEF <45%vs CT-RVEF ≥45%
HR 2.99 (95% CI 1.65–5.41); P = 0.001
Observational data: associations, not effects.
Further findings
Procedural success and in-hospital mortality
- Comparable between CT-RVEF <45% and ≥45%
Procedural success (residual TR ≤2+ at discharge) and composite outcome, by CT-RVEF
- Procedural success associated with decreased risk with CT-RVEF ≥45%; attenuated with CT-RVEF <45%
- P for interaction = 0.035
Original publication
Right ventricular ejection fraction assessed by computed tomography in patients undergoing transcatheter tricuspid valve repair. Eur Heart J Cardiovasc Imaging. Published 26 May 2023. doi:10.
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