Valvular & structural heart disease
Arrhythmic Mitral Valve Prolapse With Only Mild or Moderate Mitral Regurgitation: Characterization of Myocardial Substrate
Authors' conclusion
Most patients with degenerative MVP, ventricular ectopy, and mild or moderate MR show myocardial inflammation that is concordant with myocardial scar.
Study context
- Population
- Patients with degenerative mitral valve prolapse (MVP) and only mild or moderate mitral regurgitation (MR), recruited in a cardiac electrophysiology clinic10 [83%] complex ventricular ectopy
- Participants
- 12 patients
- Outcome
- Myocardial inflammation/fibrosis on hybrid PET/MRI
Methodological detailshybrid positron emission tomography (PET)/magnetic resonance imaging (MRI)
- Hybrid PET/MRI
Main finding
As reported in the abstract
- PET-positive (focal or focal-on-diffuse 18F-FDG uptake)
- 83% (n = 10)
- PET/MRI-positive (FDG uptake coexisting with late gadolinium enhancement)
- 75% (n = 9)
- Abnormal T1
- 58% (n = 7)
- Abnormal T2
- 25% (n = 3)
- Abnormal extracellular volume (ECV)
- 16% (n = 2)
Observational data: associations, not effects.
Original publication
Arrhythmic Mitral Valve Prolapse With Only Mild or Moderate Mitral Regurgitation: Characterization of Myocardial Substrate. JACC Clin Electrophysiol. Published 24 May 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →