Prevention & lipids

Risk and incidence of cardiovascular disease associated with polycystic ovary syndrome

Eur J Prev CardiolPublished Systematic review and meta-analysis with population attributable fraction modelling

Authors' conclusion

Women with PCOS have a significantly increased risk of CVD.

Study context

Population
Women; global burden 1990–2019five databases
Comparison
Polycystic ovary syndrome (PCOS) vs no PCOS
Outcome
Risk of CVD in women with PCOS
Methodological detailsGlobal Burden of Diseases 2019 data
  • Global Burden of Diseases 2019 data

Pooled result

As reported in the abstract

CVD risk
PCOS vs No PCOSPooled relative risk (95% CI)
All ages
1.51(1.36–1.69)
10- to 54-year-olds
1.37(1.17–1.59)

Further pooled results

Global PCOS-associated cardiovascular disease (CVD) cases, all ages · 1990 to 2019

Cases rose from 102 530 to 235 560

Most affected region in 2019

East Asia and the Pacific
108 430 (66 090-166 150)

Temporal trend of PCOS-associated CVD age-standardized rate (ASIR) (estimated annual percentage change (EAPC))

South Asia, highest increase
2.61% (2.49-2.73)
10–54 age group
0.49% (0.41-0.56)
All-age group
0.34 (0.27-0.42)
Middle- or low-middle sociodemographic index countries had higher increase trend over 30 years

Original publication

Risk and incidence of cardiovascular disease associated with polycystic ovary syndrome. Eur J Prev Cardiol. Published 19 February 2024. doi:10.1093/eurjpc/zwae066

Composed by AI from the published abstract and checked against it. How Briefs are made →

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