Arrhythmias & electrophysiology
Risk stratification for the occurrence of ventricular fibrillation in patients with early repolarization syndrome
Authors' conclusion
The occurrence of VF in patients with ERS may be associated with conduction abnormalities such as QRS widening, fQRS, high T/R ratio, positive late potentials, and pilsicainide test results.
Study context
- Population
- Patients with early repolarization syndrome (ERS)
- Participants
- 44 patients
- Exposure
- Ventricular fibrillation (VF) vs non-VF during follow-up
- VFn = 16
- non-VFn = 28reference
- Outcome
- VF during follow-up (predictive value of ECG markers)
Main finding
As reported in the abstract
ECG markers, VF vs non-VF
- VF group: longer QRS interval, more fragmented QRS (fQRS), higher T/R voltage ratio
- Wide J waves more prevalent in VF group; other J-wave markers did not differ
- Positive late potentials on signal-averaged electrocardiogram (ECG) more frequent in VF group
- No patient showed spontaneous Brugada syndrome on ECG; VF group frequently showed pilsicainide-induced ST-segment elevation
- These ECG markers significantly associated with VF during follow-up
- Multiple ECG factors (wide QRS or fQRS, wide J waves, high T/R ratio): worse prognosis than without multiple factors
Observational data: associations, not effects.
Original publication
Risk stratification for the occurrence of ventricular fibrillation in patients with early repolarization syndrome. Heart Rhythm. Published 6 May 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →