Arrhythmias & electrophysiology
Vagal response is involved in the occurrence of ventricular fibrillation in patients with early repolarization syndrome
Main finding · ERSResult — go to the resultHazard ratio 1.52 95% CI 1.031–3.061Authors' conclusion
Our findings suggest that in patients with ERS, an exaggerated vagal response, as represented by increased BaReS indices, may be involved in the risk of VF occurrence.
Study context
- Population
- Patients with early repolarization syndrome (ERS) or Brugada syndrome (BruS) who received an ICD
- Exposure
- Recurrent ventricular fibrillation (VF) vs nonrecurrent VF in ERS and BruS
- ERSn = 16
- BruSn = 34
- Recurrent VFn = 20
- Outcome
- Relationship between VF occurrence and autonomic nervous activity (baroreflex sensitivity, heart rate variability)
Main finding
ERS
Hazard ratio
1.52
95% CI 1.031–3.061
P = 0.032
High BaReS
HR 1.52 (95% CI 1.031–3.061); P = 0.032
As reported in the abstract
Observational data: associations, not effects.
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Vagal response is involved in the occurrence of ventricular fibrillation in patients with early repolarization syndrome. Heart Rhythm. Published 2 March 2023. doi:10.
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