Arrhythmias & electrophysiology
Safety and Feasibility of Pulsed-Field Ablation in Patients With Mechanical Prosthetic Valves
Authors' conclusion
PFA in patients with mechanical valves appears safe, but careful catheter handling is essential to avoid electromagnetic interference hindering PFA delivery.
Study context
- Population
- Patients with mitral and/or aortic mechanical valve replacement undergoing endocardial AF ablation with pulsed-field ablation (PFA)
- Participants
- 30 patients
- Outcome
- Feasibility (and safety) of PFA in patients with mechanical prosthetic valves
Methodological detailsconsecutive patients, 6 institutions
- Consecutive patients
- 6 institutions
Main finding
As reported in the abstract
Mean procedural time
77.5 ± 29.9 minutes
Mean left atrial dwell time
43.1 ± 21.4 minutes
Mean fluoroscopy time
14.0 ± 6.4 minutes
Observational data: associations, not effects.
Further findings
- Mean procedural time
- 77.5 ± 29.9 minutes
- Mean left atrial dwell time
- 43.1 ± 21.4 minutes
- Mean fluoroscopy time
- 14.0 ± 6.4 minutes
Safety
- Patients with electromagnetic interference of the PFA catheter adjacent to the mitral prosthesis, without clinical implications
- 1
- No periprocedural or 1-month postablation major or minor complications
- No prosthetic valve dysfunction on postprocedural transthoracic echocardiography
- No energy delivery to the mitral edge of the isthmus possible despite multiple catheter repositioning attempts
Original publication
Safety and Feasibility of Pulsed-Field Ablation in Patients With Mechanical Prosthetic Valves. JACC Clin Electrophysiol. Published 20 November 2024. doi:10.
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