Arrhythmias & electrophysiology
Safety, Efficacy, and Mid-Term Outcomes of Pulsed Field Ablation for Cavotricuspid Isthmus–Dependent Flutter: Real-World Data From a Major Health System Registry
Authors' conclusion
Pulsed field ablation appears to be a feasible and effective strategy for CTI-dependent AFL.
Study context
- Population
- Consecutive patients undergoing pulsed field ablation for cavotricuspid isthmus (CTI)-dependent atrial flutter, January 2024–March 2025median age 69.5 y
- Participants
- 132 patients
- Outcome
- Acute procedural success, periprocedural complications and CTI-dependent AFL recurrence
- Follow-up
- During
Methodological detailsconsecutive patients, registry
- Consecutive patients
- Registry
Main finding
As reported in the abstract
Acute CTI block achieved
99.2%
Adjunctive radiofrequency ablation required to complete the line
8
Typical atrial flutter (AFL) recurrence (median follow-up 114 days, n=131)
5
3.8%
6-month typical AFL-free survival estimate
93.6%
Observational data: associations, not effects.
Further findings
Catheter used
- Farawave
- 93.9%
- PulseSelect
- 4.5%
- Sphere-9
- 1.5%
Safety
Periprocedural complications
- Transient ST-segment elevation
- 2
- Transient conduction disturbances
- 3
Original publication
Safety, Efficacy, and Mid-Term Outcomes of Pulsed Field Ablation for Cavotricuspid Isthmus–Dependent Flutter: Real-World Data From a Major Health System Registry. Circ Arrhythm Electrophysiol. Published 2 December 2025. doi:10.
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