Scoring System-Based Approach for Positive Intracoronary Acetylcholine Provocation Tests: The Original and Modified ABCD Scores
Authors' conclusion
The original ABCD score was predictive of VSA in this external validation study with modest diagnostic accuracy, while the modified ABCD score achieved better predictivity for identifying patients with VSA.
Study context
- Population
- Patients undergoing acetylcholine (ACh) provocation tests for diagnosing vasospastic angina (VSA), May 2012 to September 2023patients undergoing ACh provocation tests
- Participants
- 723 patients
- Index test or model
- Modified vs original ABCD score for positive ACh provocation test results
- Target condition
- positive ACh provocation test (ie, VSA)
Performance
As reported in the abstract
| Test or model | Area under the curve |
|---|---|
| Modified ABCD score | 0.65 |
| Original ABCD score | 0.55 |
Area under the curve
Modified ABCD score0.65
Original ABCD score0.55
- Modified ABCD score vs original ABCD score: P < 0.001 — 0.65 vs 0.55
Further findings
Original ABCD score for positive ACh tests (ROC analysis)
- Original ABCD score was significantly predictive of positive ACh tests
Positive ACh provocation test results
- Patients with positive ACh provocation test results
- 383 (53.0%)
Original publication
Scoring System-Based Approach for Positive Intracoronary Acetylcholine Provocation Tests: The Original and Modified ABCD Scores. JACC Adv. Published 14 May 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →