A series of randomized trials of behavioral economic interventions to increase racial and ethnic diversity of research participants: Rationale and design of ITERATE
Study context
- Population
- Patients eligible for enrollment in the Penn Medicine BioBank (PMBB): ≥ 1 encounter with the University of Pennsylvania Health System in the past 3 months, a phone number able to receive text messages or a valid email address on file, no history of consenting to or declining enrollment in the PMBB, and able to provide their own consent
- Planned comparison
- Different messaging strategies informed by behavioral economic theory on the enrollment of Black and Hispanic individuals into the Penn Medicine BioBank (PMBB)
- Primary endpoint
- Enrollment fraction (number of participants who enroll in the PMBB divided by the total number who received an outreach message), compared between arms among both Black and Hispanic patients
Methodological detailsRandomized clinical trials (RCTs), rationale and design, iterative: "winning" strategies in earlier RCTs incorporated as "standard of care" in subsequent RCTs, at least 50% of participants Black or Hispanic in each RCT
- RCTs
- Rationale and design
- Iterative: "winning" strategies in earlier RCTs incorporated as "standard of care" in subsequent RCTs
- At least 50% of participants Black or Hispanic in each RCT
No results yet. This paper sets out the design of a trial; its results are to come.
Original publication
A series of randomized trials of behavioral economic interventions to increase racial and ethnic diversity of research participants: Rationale and design of ITERATE. Am Heart J. Published 29 March 2025. doi:10.
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