Arrhythmias & electrophysiology
Severity of Tricuspid Regurgitation Predicts Risk of Recurrence of Atrial Fibrillation After Pulmonary Vein Isolation
Authors' conclusion
In AF patients undergoing PVI, the presence of advanced TR, particularly without improvement 6 months after the procedure, was associated with an increased risk of AF recurrences.
Study context
- Population
- Atrial fibrillation (AF) patients undergoing pulmonary vein isolation (PVI)
- Participants
- 320 patients
- Exposure
- Patients with advanced tricuspid regurgitation (TR) vs patients without advanced TR
- Outcome
- Advanced TR at baseline
- Follow-up
- Baseline
Methodological detailspropensity-score matching
- Propensity-score matching
Main finding
As reported in the abstract
Advanced TR at baseline
13.1%
Observational data: associations, not effects.
Further findings
| Outcome | Hazard ratio (95% CI) | P value | |
|---|---|---|---|
| Recurrent AF, TR at baseline as predictorAfter propensity-score matching · propensity-score matching | 2.2 (1.1–4.9) | P = 0.045 | |
| 0.20.5125Hazard ratio (log scale) |
Proportion of patients with advanced TR · 6 months after PVI
- Decreased from baseline to 6 months
- 13.1% to 7.2%
- P
- P < 0.001
Right atrial (RA) area at baseline, with vs without post-interventional improvement of advanced TR
- RA area, with improvement vs without improvement
- 20.2 ± 4.4 vs. 26.6 ± 8.3 cm
AF recurrence
- Advanced TR, particularly without improvement during follow-up, increased the risk of AF recurrences compared with patients without advanced TR
Advanced MR and AF risk
- Advanced MR was not associated with increased risk of AF
Original publication
Severity of Tricuspid Regurgitation Predicts Risk of Recurrence of Atrial Fibrillation After Pulmonary Vein Isolation. ESC Heart Fail. Published 26 March 2025. doi:10.
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