Heart failure & cardiomyopathies

Sex and Age Characteristics in Acute or Chronic Myocarditis A Descriptive, Multicenter Cohort Study

JACC AdvPublished Retrospective cohort study

Authors' conclusion

In this study, we found that sex differences in myocarditis and clinical features of myocarditis were age-dependent.

Study context

Population
Patients with acute or chronic myocarditis, 3 centres in Berlin, Germany (2005–2021) and US National Inpatient Sample (2010–2019)6,023 Berlin
Exposure
Age categories in patients with myocarditis
Outcome
Sex distribution and clinical outcomes (hospital mortality, length of stay, medical complication rates) by age
Methodological detailsmulticentre, Berlin cohort (3 centres) and US National Inpatient Sample
  • Multicentre
  • Berlin cohort (3 centres) and US National Inpatient Sample

Main finding

As reported in the abstract

Sex distribution by age category

Males

Females

Observational data: associations, not effects.

Further findings

OutcomeP value
Laboratory values, prepubescent vs young adults (Berlin cohort)Prepubescent vs Young adults · higher leukocytesP < 0.001
Laboratory values, prepubescent vs young adults (Berlin cohort)Prepubescent vs Young adults · higher antistreptolysin antibodyP < 0.001
Laboratory values, prepubescent vs young adults (Berlin cohort)Prepubescent vs Young adults · higher NT-proBNPP < 0.001

Original publication

Sex and Age Characteristics in Acute or Chronic Myocarditis A Descriptive, Multicenter Cohort Study. JACC Adv. Published 20 February 2024. doi:10.1016/j.jacadv.2024.100857

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