Arrhythmias & electrophysiology
Sex- and age-specific differences in the use of antiarrhythmic therapies among atrial fibrillation patients: a nationwide cohort study
Authors' conclusion
Women used more AAD than men in all age groups but underwent fewer cardioversion and ablation procedures when aged <65 years.
Study context
- Population
- Patients with new-onset atrial fibrillation (AF) in Finland, 2007–201850% females
- Participants
- 229,565 patients
- Exposure
- Women vs men
- Outcome
- Initiation of antiarrhythmic therapies: antiarrhythmic drugs, cardioversion or catheter ablation
Methodological detailsnationwide, registry-based linkage study
- Nationwide
- Registry-based linkage study
Main finding
As reported in the abstract
Antiarrhythmic therapy use by sex and age group
Women vs MenAdjusted subdistribution hazard ratio (95% CI)
Antiarrhythmic drugs, all age groups
1.223(1.187–1.261)
Cardioversion, aged <65 years
0.722(0.695–0.749)
Cardioversion, aged ≥ 75 years
1.166(1.108–1.227)
Ablation, aged <65 years
0.908(0.826–0.998)
Ablation, aged ≥75 years
0.521(0.354–0.766)
Observational data: associations, not effects.
Further findings
Baseline age
Original publication
Sex- and age-specific differences in the use of antiarrhythmic therapies among atrial fibrillation patients: a nationwide cohort study. Europace. Published 9 October 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →