Sex differences in statin treatment after myocardial infarction in Denmark: a time-trend study utilizing Danish national registries
Authors' conclusion
A smaller proportion of females received statins than males after a MI. Disparities in treatment persisted over the years.
Study context
- Population
- Patients with first-time Myocardial Infarction (MI) in Denmark, 2000–2024, not on lipid-lowering drugs in the 180 days before MI
- Participants
- 154,591 patients
- Exposure
- Females vs males
- Outcome
- Statin treatment initiation
- Follow-up
- Within 180 days
Methodological detailsnationwide Danish registries, time-trend, multivariable Poisson regression
- Nationwide Danish registries
- Time-trend
- Multivariable Poisson regression
Main finding
As reported in the abstract
Statin initiation
Females vs MalesRelative risk (CI)P value
Unadjusted
0.75(0.74–0.76)
P < 0.001Adjusted for age groups and year interval
0.87(0.86–0.87)
Further adjusted for baseline characteristics
0.91(0.85–99)
Observational data: associations, not effects.
Further findings
Statin initiation by year interval, females ≥40 years
- Significantly lower proportions in females in every year interval
- P < 0.001 for all
Relative sex difference over time, within age groups
- Increased from 2000-2002 until 2015-2019, then decreased to 2020-2024 (60-69-year-olds: decrease from 2010-2014)
Original publication
Sex differences in statin treatment after myocardial infarction in Denmark: a time-trend study utilizing Danish national registries. Eur J Prev Cardiol. Published 29 August 2026. doi:10.
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