Heart failure & cardiomyopathies

Sex-specific heart failure burden across the United States: Global burden of disease 1990-2019

Am Heart JPublished Cross-sectional study

Authors' conclusion

The burden of HF in the US is high, although the magnitude of this burden varies according to age, sex, state, and region. There is a significant increase in the absolute number of individuals with HF, especially among women >70 years, expected to continue due to the aging population.

Study context

Population
US population, by sex, state and region, 1990–2019 (heart failure (HF) defined by symptom-based criteria)
Exposure
Females vs males
Outcome
Age-adjusted HF prevalence and YLD rates per 100,000 individuals
Methodological detailsGlobal Burden of Disease 2019 data, US states and regions, 1990–2019
  • Global Burden of Disease 2019 data
  • US states and regions
  • 1990–2019

Main finding

As reported in the abstract

Age-adjusted HF prevalence per 100,000 · 2019

Observational data: associations, not effects.

Further findings

HF prevalence trends over time (US) · 1990–2019

Cyclic fluctuations in HF prevalence, peaks mid-1990s and around 2010, lowest points around 2000 and 2018

States with increased HF prevalence, 1990-1994 vs 2015-2019

States with increased female HF prevalence
10
States with increased male prevalence
4

Absolute number with HF, age >70 years · 1990–2019

Absolute number with HF higher in females; count doubled between 1990 and 2019

Relative decline in HF burden by region

Western states had the greatest relative decline in HF burden, in both sexes

Original publication

Sex-specific heart failure burden across the United States: Global burden of disease 1990-2019. Am Heart J. Published 16 December 2023. doi:10.1016/j.ahj.2023.12.008

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