Acute cardiac care & resuscitation

Shock Stages in Cardiac Surgical Patients: Implications for Post-Cardiotomy Shock and Mortality

JACC AdvPublished Retrospective analysis of Society of Thoracic Surgeons adult cardiac surgery database

Authors' conclusion

CS-SCAI facilitates risk prognostication prior to and following cardiac surgery. Transitions of stage are associated with a spectrum of high mortality and could be used to better define post-cardiotomy shock.

Study context

Population
Adult cardiac surgical patients in the Society of Thoracic Surgeons adult cardiac surgery database, January 2015 to December 2019patients included
Participants
1,164,015 patients
Exposure
CS-SCAI stages applied at various time points and correlated with survival
Outcome
Preoperative stage distribution and 30-day mortality
Follow-up
30-day

Main finding

As reported in the abstract

30-day
GroupValuePreoperative share
CS-SCAI A1.2%35.9%
CS-SCAI B2.12%54.9%
CS-SCAI C9.84%8.3%
CS-SCAI D17.06%0.7%
CS-SCAI E42.1%0.2%

Value

CS-SCAI A1.2%
CS-SCAI B2.12%
CS-SCAI C9.84%
CS-SCAI D17.06%
CS-SCAI E42.1%

Preoperative share

CS-SCAI A35.9%
CS-SCAI B54.9%
CS-SCAI C8.3%
CS-SCAI D0.7%
CS-SCAI E0.2%

Observational data: associations, not effects.

Further findings

Predictors of mortality

In the preoperative and postoperative setting, CS-SCAI stage was the strongest predictor of mortality

Transition to worsened CS-SCAI stage postoperatively · 30-day

Patients with transition to worsened stage
6,508
30-day mortality among those patients
51.6%

Predictors of stage transition

Strongest predictors: cardiopulmonary bypass time, preoperative CS-SCAI stage, and aortic cross clamp time

Original publication

Shock Stages in Cardiac Surgical Patients: Implications for Post-Cardiotomy Shock and Mortality. JACC Adv. Published 10 July 2025. doi:10.1016/j.jacadv.2025.101975

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