Acute cardiac care & resuscitation
Short- and long-term outcomes of patients with acute myocardial infarction complicated by cardiac arrest: a nationwide cohort study 2013–22
Authors' conclusion
In this large, contemporary cohort of AMI patients, in-hospital mortality of patients with OHCA or IHCA was still high. Among patients surviving to hospital discharge, long-term mortality was comparable between OHCA and AMI without CA, while the outcome of patients with IHCA was significantly worse.
Study context
- Population
- Acute myocardial infarction (AMI) patients admitted to hospitals in Norway 2013–22, Norwegian Myocardial Infarction Registry35% women
- Participants
- 105,439 patients
- Exposure
- AMI with out-of-hospital cardiac arrest (OHCA) or in-hospital cardiac arrest (IHCA) vs AMI without cardiac arrest (CA)
- OHCAn = 3,638
- IHCAn = 2,559
- Outcome
- In-hospital and long-term mortality
Methodological detailsnationwide, registry-based
- Nationwide
- Registry-based
Main finding
As reported in the abstract
In-hospital mortality
| Group | Value | 5-year cumulative mortality |
|---|---|---|
| OHCA | 28% | 48% (95% CI 46-50%) |
| IHCA | 49% | 69% (95% CI 67-71%) |
| AMI without CA | 5% | 35% (95% CI 34-35%) |
Value
OHCA28%
IHCA49%
AMI without CA5%
5-year cumulative mortality
OHCA48% (95% CI 46-50%)
IHCA69% (95% CI 67-71%)
AMI without CA35% (95% CI 34-35%)
Observational data: associations, not effects.
Further findings
| Outcome | Estimate | |
|---|---|---|
| Long-term mortality among survivors to hospital dischargeOHCAvs AMI without CA | adjusted HR 1.04 (95% CI 0.96–1.13) | |
| Long-term mortality among survivors to hospital dischargeIHCAvs AMI without CA | age-adjusted HR 1.31 (95% CI 1.19–1.45) | |
| 0.512Ratio (log scale) |
Original publication
Short- and long-term outcomes of patients with acute myocardial infarction complicated by cardiac arrest: a nationwide cohort study 2013–22. Eur Heart J Acute Cardiovasc Care. Published 23 October 2024. doi:10. 1093/ ehjacc/ zuae121
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