Acute cardiac care & resuscitation

Short- and long-term outcomes of patients with acute myocardial infarction complicated by cardiac arrest: a nationwide cohort study 2013–22

Eur Heart J Acute Cardiovasc CarePublished Retrospective cohort study

Authors' conclusion

In this large, contemporary cohort of AMI patients, in-hospital mortality of patients with OHCA or IHCA was still high. Among patients surviving to hospital discharge, long-term mortality was comparable between OHCA and AMI without CA, while the outcome of patients with IHCA was significantly worse.

Study context

Population
Acute myocardial infarction (AMI) patients admitted to hospitals in Norway 2013–22, Norwegian Myocardial Infarction Registry35% women
Participants
105,439 patients
Exposure
AMI with out-of-hospital cardiac arrest (OHCA) or in-hospital cardiac arrest (IHCA) vs AMI without cardiac arrest (CA)
  • OHCAn = 3,638
  • IHCAn = 2,559
Outcome
In-hospital and long-term mortality
Methodological detailsnationwide, registry-based
  • Nationwide
  • Registry-based

Main finding

As reported in the abstract

In-hospital mortality
GroupValue5-year cumulative mortality
OHCA28%48% (95% CI 46-50%)
IHCA49%69% (95% CI 67-71%)
AMI without CA5%35% (95% CI 34-35%)

Value

OHCA28%
IHCA49%
AMI without CA5%

5-year cumulative mortality

OHCA48% (95% CI 46-50%)
IHCA69% (95% CI 67-71%)
AMI without CA35% (95% CI 34-35%)

Observational data: associations, not effects.

Further findings

OutcomeEstimate
Long-term mortality among survivors to hospital dischargeOHCAvs AMI without CAadjusted HR 1.04 (95% CI 0.96–1.13)
Long-term mortality among survivors to hospital dischargeIHCAvs AMI without CAage-adjusted HR 1.31 (95% CI 1.19–1.45)

Original publication

Short- and long-term outcomes of patients with acute myocardial infarction complicated by cardiac arrest: a nationwide cohort study 2013–22. Eur Heart J Acute Cardiovasc Care. Published 23 October 2024. doi:10.1093/ehjacc/zuae121

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