Arrhythmias & electrophysiology
Slowly conducting anatomic isthmuses of tetralogy of Fallot: An opportunity for “prophylactic” ventricular tachycardia ablation
Authors' conclusion
Prophylactic SCAI ablation is associated with fewer ICD implantations and a reduction in incident arrhythmic events without ablation-related complications.
Study context
- Population
- Patients with repaired tetralogy of Fallot undergoing risk stratification electrophysiologic studies
- Participants
- 92 patients
- Exposure
- Prophylactic SCAI ablation vs historical strategy
- Prophylacticn = 57
- Historicaln = 35reference
- Outcome
- Composite of:
- Arrhythmic death
- Cardiac arrest
- Sustained VT
- ICD complication
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
| Group | Value | Median follow-up |
|---|---|---|
| Prophylactic | 0 events | 21 months (IQR 8-35 months) |
| Historical | 29% | 125 months (IQR 90-142 months) |
Value
Prophylactic0 events
Historical29%
Median follow-up
Prophylactic21 months (IQR 8-35 months)
Historical125 months (IQR 90-142 months)
- Prophylactic vs Historical: P = 0.017
Observational data: associations, not effects.
Further findings
Inducible VT · Prophylactic: before ablation
Events
| Outcome | Prophylactic | Historical |
|---|---|---|
| ICD implantation | 1 | 11 |
- Slowly conducting anatomic isthmuses (SCAIs) identified or ablated (Prophylactic)
- 58% · 33 of 57
Safety
- No ablation-related complications
Original publication
Slowly conducting anatomic isthmuses of tetralogy of Fallot: An opportunity for “prophylactic” ventricular tachycardia ablation. Heart Rhythm. Published 17 November 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →