Ventricular Tachycardia Substrates in Children and Young Adults With Repaired Tetralogy of Fallot
Authors' conclusion
In young patients with rTOF, SCAI 3 is the dominant substrate for VT.
Study context
- Population
- Patients with repaired tetralogy of Fallot aged <30 years undergoing electroanatomical mapping and programmed electrical stimulation, 2005–2022
- Participants
- 55 patients
- Outcome
- Characterization of VT substrates (slow conducting anatomical isthmuses)
Methodological detailsconsecutive patients, Identified ventricular tachycardia (VT) substrates targeted by ablation
- Consecutive patients
- Identified VT substrates targeted by ablation
Main finding
As reported in the abstract
SCAI 3 identified (no other SCAI present)
SCAI 3 identified
16
29%
Observational data: associations, not effects.
Further findings
Inducible monomorphic VT
- Monomorphic VT inducible
- 8
- Inducible VT related to SCAI 3
- 7
Factors associated with SCAI 3 (univariable analysis)
- RV-to-pulmonary artery conduit/early pulmonary valve replacement (PVR), ventriculotomy and complex TOF associated with SCAI 3
- Univariable analysis
VT recurrence after ablation · median follow-up 5.3 years
- VT recurred
- 2
Death · median follow-up 5.3 years
- Deaths
- 0
Original publication
Ventricular Tachycardia Substrates in Children and Young Adults With Repaired Tetralogy of Fallot. JACC Clin Electrophysiol. Published 25 September 2024. doi:10.
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