Arrhythmias & electrophysiology

Social Determinants of Health and Disparities in Diagnosis-to-Ablation Time for Atrial Fibrillation

JACC Clin ElectrophysiolPublished Retrospective cohort study

Authors' conclusion

Greater SDOH burden is associated with significant delays in accessing AF ablation.

Study context

Population
Patients undergoing first atrial fibrillation (AF) ablation, Hopkins AF Ablation Registry (2014–2023)
Participants
1,025 patients
Exposure
Higher vs lower Area Deprivation Index
Outcome
AF diagnosis-to-ablation time (DAT) by ADI
Methodological detailsregistry-based
  • Registry-based

Main finding

As reported in the abstract

DAT per 10-unit increase in ADI percentile

Increase in diagnosis-to-ablation time (DAT) per 10-unit increase in Area Deprivation Index (ADI) percentile

6.96%

95% CI 1.02–1.12P = 0.003

Delay per 10-unit increase in ADI percentile

3.83 months

95% CI 1.27–6.39

Observational data: associations, not effects.

Further findings

DAT by age group, sex or race (subgroups)

No significant interactions by age group, sex or race

Anticoagulant prescription at discharge (eligible patients)

No significant association with ADI percentile
P = 0.097

Original publication

Social Determinants of Health and Disparities in Diagnosis-to-Ablation Time for Atrial Fibrillation. JACC Clin Electrophysiol. Published 28 August 2025. doi:10.1016/j.jacep.2025.07.006

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