Soluble ST2 in plasma is associated with post-procedural no-or-slow reflow after primary percutaneous coronary intervention in ST-elevation myocardial infarction
Authors' conclusion
In patients with STEMI, the sST2 level at admission before coronary angiography is independently associated with the post-procedural no-or-slow-reflow phenomenon.
Study context
- Population
- Patients with verified ST-elevation myocardial infarction (STEMI) undergoing primary PCI, two tertiary heart centreswith available thrombolysis in myocardial infarction (TIMI) flow
- Participants
- 1,607 patients
- Exposure
- No-or-slow reflow vs normal reflow after primary PCI
- No-or-slow reflown = 87
- Normal reflown = 1,520reference
- Outcome
- Association of pre-intervention plasma sST2 with post-procedural no-or-slow reflow
Methodological detailsconsecutive patients, two tertiary heart centres
- Consecutive patients
- Two tertiary heart centres
Main finding
As reported in the abstract
Pre-procedural sST2 and post-procedural no-or-slow reflow · admission, before angiography
- No-or-slow reflow vs Normal reflow: P < 0.001
Observational data: associations, not effects.
Further findings
All-cause mortality · 30 days
P = 0.006
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Soluble ST2 in plasma is associated with post-procedural no-or-slow reflow after primary percutaneous coronary intervention in ST-elevation myocardial infarction. Eur Heart J Acute Cardiovasc Care. Published 10 November 2022. doi:10.
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