Coronary disease & ACSCohort study
Standard modifiable risk factors among patients undergoing percutaneous coronary intervention: prevalence and impact
- Retrospective cohort study
- single-centre
Authors' conclusion
Comprehensive SMuRF control before PCI remains infrequent, though it is associated with lower MACE rates.
Study context
- Population
- Patients undergoing percutaneous coronary intervention (PCI) at a single tertiary-care centre, 2012–2023; SMuRF control by pre-procedural SBP <140 mmHg, fasting glucose <126 mg/dL or HbA1c < 7%, LDL <100 mg/dL, non-smoker
- Participants
- 19,651 patients
- Exposure
- Number of controlled standard modifiable risk factors
- 4-CRFn = 5,876reference
- 3-CRFn = 8,199
- 2-CRFn = 4,415
- ≤1-CRFn = 1,161
- Outcome
- MACE:
- All-cause mortality
- MI
- Stroke
- Follow-up
- One-year post-PCI
Main finding
As reported in the abstract
Each group vs 4-CRFAdjusted hazard ratio (95% CI)
3-CRF
1.17(0.98–1.40)
2-CRF
1.39(1.14–1.69)
≤1-CRF
1.48(1.10–2.00)
Observational data: associations, not effects.
Further findings
Prevalence of controlled risk factors
Major adverse cardiovascular events (MACE) by glycaemic control
- Glycaemic control had the most significant association with lower MACE
- adjHR 0.56 (95% CI 0.49-0.65)
Original publication
Standard modifiable risk factors among patients undergoing percutaneous coronary intervention: prevalence and impact. Eur Heart J. Published 1 June 2026. doi:10.1093/eurheartj/ehag254
Summarised from the published abstract; every number is checked against it