Arrhythmias & electrophysiology
Strength–duration curves for left bundle branch area pacing
Authors' conclusion
The obtained strength-duration curves for LBBP and LVSP provide insights to optimal programming of left bundle branch area pacing devices with regard to PD, voltage amplitude, battery longevity, and selective capture.
Study context
- Population
- Patients with permanent left bundle branch pacing (LBBP)
- Participants
- 141 LBBP patients
- Comparison
- LBBP vs LVSP
- His-bundle pacing (HBP)n = 127reference
- Outcome
- Strength–duration curves with chronaxie and rheobase values for LBBP and LVSP
Methodological detailsCapture thresholds assessed at 6 different pulse duration (PDs)
- Capture thresholds assessed at 6 different PDs
Main finding
As reported in the abstract
| Group | Chronaxie | Rheobase |
|---|---|---|
| LBBP | 0.38 ms | 0.27 V |
| LVSP | 0.39 ms | 0.27 V |
| HBP | 0.53 ms | 0.26 V |
Chronaxie
LBBP0.38 ms
LVSP0.39 ms
HBP0.53 ms
Rheobase
LBBP0.27 V
LVSP0.27 V
HBP0.26 V
- LBBP vs HBP: P < 0.001 — chronaxie lower with LBBP
Further findings
Narrow zone of selective LBBP capture
- At PD 0.06 ms
- 19%
- At PD 0.03 ms
- 41%
Battery current drain (safety margin +1 V)
- Lowest drain at PD
- 0.2 ms
Original publication
Strength–duration curves for left bundle branch area pacing. Heart Rhythm. Published 15 May 2024. doi:10.
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