Arrhythmias & electrophysiology
Subcutaneous Implantable Defibrillators in Young Patients: Arrhythmias, Complications, and Physical Activity
Authors' conclusion
Young S-ICD patients often lead active lifestyles and participate in sports. Higher activity levels were not associated with increased implantable cardioverter defibrillator-related complications or increased risk of implantable cardioverter defibrillator shocks.
Study context
- Population
- Young-adult (15–65 years) S-ICD patients; physical activity evaluated with IPAQ (International Physical Activity Questionnaire)S-ICD recipients (77% men, age, 46±14 years)
- Participants
- 602 participants
- Exposure
- Association between lifestyle and recreational sports on S-ICD safety and shocks
- Athletesn = 163
- Outcome
- Safety end point of arrhythmia- or device-related complications
- Follow-up
- During (47.3 [interquartile range, 27.0-67.6] months)
Main finding
As reported in the abstract
Patients reaching the safety end point
23 patients
3.8%
Observational data: associations, not effects.
Further findings
Physical activity category according to the IPAQ
- Appropriate shocks · moderately active subjects vs inactive subjects
- P = 0.12
- Appropriate shocks · highly active subjects vs inactive subjects
- P = 0.11
- Appropriate shocks · athletes vs nonathletes · nonsignificant lower incidence in athletes
- P = 0.06
- Appropriate shocks — Patients with appropriate shocks
- Forty-four patients had 87 appropriate shocks
- Inappropriate shocks · moderately active subjects vs inactive subjects · similar incidence
- P = 0.92
- Inappropriate shocks · highly active subjects vs inactive subjects · similar incidence
- P = 0.88
- Inappropriate shocks — Patients with inappropriate shocks
- Thirty-nine patients had 46 inappropriate shocks
- Physical activity category according to the IPAQ — Among moderately/highly active subjects, recreational athletes
- 163 (27.1%)
- Appropriate shocks: nonsignificantly lower incidence with moderately active subjects; multivariate analysis
- Appropriate shocks: nonsignificantly lower incidence with highly active subjects; multivariate analysis
Original publication
Subcutaneous Implantable Defibrillators in Young Patients: Arrhythmias, Complications, and Physical Activity. Circ Arrhythm Electrophysiol. Published 24 February 2025. doi:10. 1161/ circep. 124. 013365
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