Arrhythmias & electrophysiology
Superior Vena Cava Isolation With Cryoballoon in AF Ablation: Randomized CAVAC AF Trial
Authors' conclusion
The addition of SVC ablation to PVI did not enhance freedom from atrial tachyarrhythmia at 12 months, and it led to increased complications.
Study context
- Population
- Patients with paroxysmal or non-long-standing persistent AF undergoing catheter ablation
- Participants
- 100 patients
- Comparison
- Cryoballoon pulmonary vein isolation (PVI) plus superior vena cava (SVC) ablation vs PVI alone
- Primary endpoint
- Freedom from any atrial tachyarrhythmia recurrence
- Follow-up
- Between 91 and 365 days post-catheter ablation
Methodological detailsDaily ECG by mobile device to detect atrial tachyarrhythmias
- Daily ECG by mobile device to detect atrial tachyarrhythmias
Primary result
As reported in the abstract
91–365 days post-ablation
Freedom from any atrial tachyarrhythmia recurrence did not significantly differ between the 2 groups
62.9% versus 72%
P=0.41
Further findings
Median burden of atrial tachyarrhythmia
- No significant difference
- P = 0.91
Safety
Phrenic nerve paralysis
P = 0.003
Transient sinus node injury
P = 0.001
Original publication
Superior Vena Cava Isolation With Cryoballoon in AF Ablation: Randomized CAVAC AF Trial. Circ Arrhythm Electrophysiol. Published 16 December 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →