Arrhythmias & electrophysiology
Surgical ablation in non-mitral valve cardiac surgeries: a meta-analysis of early outcomes
Pooled result · Postoperative AF (POAF)Result — go to the resultRelative risk 0.73 95% CI 0.67–0.79Authors' conclusion
In this meta-analysis, SA was associated with POAF reduction in non-MV surgery. In terms of safety, it was suggested that although no difference in early mortality and postoperative stroke was observed, SA had a higher risk of pacemaker implantation than isolated non-MV surgery.
Study context
- Population
- Atrial fibrillation (AF) patients undergoing non-MV surgeryAF patients undergoing non-MV surgery, of whom 18,394 (46.7%) underwent surgical ablation (SA), 2 randomised controlled trials (RCTs) and 5 PSM studies
- Participants
- 39,348 patients
- Comparison
- Concomitant SA to isolated non-MV surgery in AF patients
- SAn = 18,394
- Outcome
- Postoperative AF (POAF)
Methodological detailsrandom effects model, 2 RCTs and 5 PSM studies
- Random effects model
- 2 RCTs and 5 PSM studies
Pooled result
As reported in the abstract
Relative risk
0.73
95% CI 0.67–0.79
SAvs isolated non-MV surgery
RR 0.73 (95% CI 0.67–0.79)
Further pooled results
Subgroup analysis RCTs vs PSM
- Significant consistency among the different designs
Safety
| Outcome | RR (95% CI) | |
|---|---|---|
| Postoperative pacemaker implantationI 2 =0%; higher risk with SA | 1.34 (1.14–1.57) | |
| Early all-cause mortalityI 2 =65% | 0.96 (0.76–1.22) | |
| Postoperative strokeI 2 =0% | 1.06 (0.89–1.26) | |
| 0.512Relative risk (log scale) |
Original publication
Surgical ablation in non-mitral valve cardiac surgeries: a meta-analysis of early outcomes. Heart. Published 7 August 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →