Valvular & structural heart disease
Surgical vs Transcatheter Treatment in Patients With Coronary Artery Disease and Severe Aortic Stenosis
Authors' conclusion
Despite a lower baseline risk, CABG + SAVR in patients with severe AS and CAD was associated with a higher rate of death and stroke compared with PCI + TAVR
Study context
- Population
- Patients with severe aortic stenosis (AS) and CAD, Spain, treated 2018–2021
- Participants
- 1,342 patients
- Exposure
- Percutaneous coronary intervention (PCI) + transcatheter aortic valve replacement (TAVR) vs coronary artery bypass grafting (CABG) + surgical aortic valve replacement (SAVR)
- PCI + TAVRn = 625
- CABG + SAVRn = 713reference
- Outcome
- All-cause mortality and stroke
- Follow-up
- 1 year
Methodological detailsnational multicentre, propensity score analysis
- National multicentre
- Propensity score analysis
Main finding
As reported in the abstract
Mortality + stroke
- Higher mortality + stroke with CABG + SAVR vs PCI + TAVR persisted at 1-year follow-up
Observational data: associations, not effects.
Further findings
Mortality + stroke, unmatched cohort · 30 days
P = 0.005
Mortality + stroke, matched cohort · 30 days · matched cohort
P = 0.002
Technical success
P = 0.008
Periprocedural mortality
P = 0.999
Original publication
Surgical vs Transcatheter Treatment in Patients With Coronary Artery Disease and Severe Aortic Stenosis. JACC Cardiovasc Interv. Published 11 November 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →