Surveillance Stress Testing After Percutaneous Intervention for Patients With Multivessel or Left Main Coronary Disease
Primary resultResult — go to the resultHazard ratio 1.09 95% CI 0.68–1.74Authors' conclusion
In high-risk patients with multivessel or left main CAD who underwent PCI, there was no incremental clinical benefit from routine surveillance functional-testing compared with standard care alone during follow-up.
Study context
- Population
- High-risk patients with multivessel or left main coronary artery disease (CAD) who underwent percutaneous coronary intervention (PCI)of 1,706 randomised
- Participants
- 1,192 patients
- Comparison
- Routine functional testing at 1 year vs standard care alone
- Functional testingn = 589
- Standard caren = 603reference
- Primary endpoint
- Composite of:
- All-cause death
- MI
- Hospitalisation for unstable angina
- Follow-up
- 2 years
Primary result
As reported in the abstract
Hazard ratio
1.09
95% CI 0.68–1.74
P = 0.73
By group
Functional testingvs Standard care
HR 1.09 (95% CI 0.68–1.74); P = 0.73
Further findings
| Outcome | HR (95% CI) | P value | |
|---|---|---|---|
| Primary outcome, multivessel disease (subgroup, n = 833) · 2 years | 1.09 (0.62–1.89) | P = 0.78 | |
| Primary outcome, left main disease (subgroup, n = 359) · 2 years | 1.09 (0.46–2.56) | P = 0.85 | |
| 0.20.5125Hazard ratio (log scale) |
- Primary outcome, multivessel disease (subgroup, n = 833): P for interaction = 0.90
- Primary outcome, left main disease (subgroup, n = 359): P for interaction = 0.90
Invasive angiography and repeat revascularisation beyond 1 year
- Increased rates with routine surveillance functional testing
Original publication
Surveillance Stress Testing After Percutaneous Intervention for Patients With Multivessel or Left Main Coronary Disease. J Am Coll Cardiol. Published 5 March 2024. doi:10.
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