Tailored hydration for the prevention of contrast-induced acute kidney injury after coronary angiogram or PCI: A systematic review and meta-analysis
Pooled result · CI-AKIResult — go to the resultRelative risk 0.56 95% CI 0.46–0.69Authors' conclusion
These results suggest that tailored hydration is superior to nontailored hydration in reducing the risk of CI-AKI and MACE in patients undergoing coronary angiography. Future trials are required to identify the optimal tailored hydration strategy.
Study context
- Population
- Patients undergoing coronary angiography for any indication
- Participants
- 4,458 patients13 studies
- Comparison
- Tailored versus nontailored hydration strategies
- Outcome
- Contrast-induced acute kidney injury (CI-AKI)
Pooled result
As reported in the abstract
Relative risk
0.56
95% CI 0.46–0.69
P < 0.00001
Tailored hydrationvs nontailored hydration
RR 0.56 (95% CI 0.46–0.69); P < 0.00001
Further pooled results
| Outcome | RR (95% CI) | P value | |
|---|---|---|---|
| MACE (main secondary outcome)I2 = 12% | 0.57 (0.42–0.78) | P = 0.0005 | |
| All-cause mortalityI2 = 0% | 0.57 (0.35–0.94) | P = 0.03 | |
| 0.20.5125Relative risk (log scale) |
Other prespecified secondary outcomes
- Not associated with a significant reduction
Risk of bias
- The overall risk of bias was moderate
Original publication
Tailored hydration for the prevention of contrast-induced acute kidney injury after coronary angiogram or PCI: A systematic review and meta-analysis. Am Heart J. Published 4 January 2025. doi:10.
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