Imaging- and physiology-guided percutaneous coronary intervention without contrast administration in advanced renal failure: a feasibility, safety, and outcome study
Authors' conclusion
In patients with advanced CKD who require revascularization, PCI may safely be performed without contrast using IVUS and physiological guidance with high procedural success and without complications.
Study context
- Population
- Patients with advanced chronic kidney disease (CKD) (creatinine 4.2 mg/dL, IQR 3.1–4.8; eGFR 16 ± 8 mL/min/1.73 m²) with clinical indication for percutaneous coronary intervention (PCI) based on a prior minimal contrast coronary angiogram
- Participants
- 31 patients
- Outcome
- Successful PCI, MACE, preserved renal function without RRT
- Follow-up
- 79 days (IQR 33-207)
Methodological detailsfeasibility, safety and outcome study, single-group
- Feasibility, safety and outcome study
- Single-group
Main finding
As reported in the abstract
- Successful PCI in all patients
- No MACE
- Preservation of renal function without need for renal replacement therapy (RRT) in all patients
Observational data: associations, not effects.
Safety
| Outcome | Values |
|---|---|
| MACE · follow-up 79 days (IQR 33-207) | Zero contrast PCI 0 events |
Original publication
Imaging- and physiology-guided percutaneous coronary intervention without contrast administration in advanced renal failure: a feasibility, safety, and outcome study. Eur Heart J. Published 7 March 2016. doi:10.
Summarised from the published abstract; every number is checked against it