Pulmonary vascular disease & thromboembolism

Temporal Trends in the Use of Computed Tomographic Pulmonary Angiography for Suspected Pulmonary Embolism in the Emergency Department : A Retrospective Analysis

Ann Intern MedPublished Retrospective cohort study

Authors' conclusion

Despite the recent validation of clinical decision rules to limit the use of CTPA, an increase in the CTPA rate along with more diagnosed PEs and especially low-risk PEs were instead observed.

Study context

Population
Patients with computed tomographic pulmonary angiography (CTPA) for suspected pulmonary embolism (PE) in the emergency department (ED), first 7 days of each odd month, January 2015–December 2019
Participants
8,970 CTPAs
Exposure
Temporal trends 2015 vs 2019
Outcome
CTPAs for suspected PE in the ED and PEs diagnosed in the ED per year, adjusted to an annual census of 100 000 ED visits
Methodological detailsmulticentre, 26 European EDs in 6 countries, Data limited to 7 days every 2 months
  • Multicentre
  • 26 European EDs in 6 countries
  • Data limited to 7 days every 2 months

Main finding

As reported in the abstract

GroupCTPA useDiagnosed PEs
2015836 per 100 000 ED visits138 per 100 000
20191112164

CTPA use

2015836 per 100 000 ED visits
20191112

Diagnosed PEs

2015138 per 100 000
2019164
  • 2019 vs 2015: P < 0.001 — CTPA use
  • 2019 vs 2015: P = 0.028 — diagnosed PEs

Observational data: associations, not effects.

Further findings

Proportion of low-risk PEs

Annual percent change
13.8% (95% CI 2.6% to 30.1%)

Ambulatory management

Annual percent change
19.3% (CI 4.1% to 45.1%)

Proportion of ICU admissions

Annual percent change
−8.9% (CI −17.1% to −0.3%)

Original publication

Temporal Trends in the Use of Computed Tomographic Pulmonary Angiography for Suspected Pulmonary Embolism in the Emergency Department : A Retrospective Analysis. Ann Intern Med. Published 23 May 2023. doi:10.7326/m22-3116

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