The Association Between Angiographically Derived Radial Wall Strain and the Risk of Acute Myocardial Infarction
Main finding · Baseline maximum RWS (RWSmax)Result — go to the resultRisk ratio 7.25 95% CI 3.94–13.37Authors' conclusion
Among angiographically mild to intermediate lesions, a high-strain pattern identified by angiography-derived RWS was associated with an increased risk of AMI events.
Study context
- Population
- Patients with ≥1 de novo mild to intermediate coronary lesion at prior angiography, hospitalized again for repeat angiography ≥1 month later
- Participants
- 44 vs 132
- Comparison
- Lesion-related acute myocardial infarction (AMI) vs matched controls without AMI
- AMIn = 44
- Controlsn = 132reference
- Outcome
- Association between angiography-derived RWS and future AMI events
Methodological detailsmatched, retrospective cohort, 3 controls per case
- Matched
- Retrospective cohort
- 3 controls per case
Main finding
Baseline maximum RWS (RWSmax)
Risk ratio
7.25
95% CI 3.94–13.37
P < 0.001
By group
RWSmax >12%
risk ratio 7.25 (95% CI 3.94–13.37); P < 0.001
As reported in the abstract
- RWSmax predictive of lesion-related AMI, AUC
- 0.83 (95% CI: 0.76-0.90; P < 0.001)
- Optimal RWSmax cutoff
- >12%
Observational data: associations, not effects.
Original publication
The Association Between Angiographically Derived Radial Wall Strain and the Risk of Acute Myocardial Infarction. JACC Cardiovasc Interv. Published 8 May 2023. doi:10. 1016/ j. jcin. 2023. 02. 012
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