Prevention & lipids

The association between daily step count and all-cause and cardiovascular mortality: a meta-analysis

Eur J Prev CardiolPublished Systematic review and meta-analysis of cohort studies

An erratum to this article was published (Eur J Prev Cardiol, 21 Dec 2023 ↗)

Authors' conclusion

This meta-analysis demonstrates a significant inverse association between daily step count and all-cause mortality and CV mortality with more the better over the cut-off point of 3867 steps/day for all-cause mortality and only 2337 steps for CV mortality.

Study context

Population
Generally healthy individuals or patients at cardiovascular (CV) risk
Participants
226,889 individuals17 cohort studies
Comparison
Higher vs lower daily step count
Outcome
All-cause mortality and CV mortality
Follow-up
Median 7.1 years
Methodological detailsrandom-effects model, dose-response analysis
  • Random-effects model
  • Dose-response analysis

Pooled result

As reported in the abstract

Hazard ratio (95% CI)P value
1000-step incrementall-cause mortality; 15% decreased risk
0.85(0.81–0.91)
P < 0.001
500-step incrementCV mortality; 7% decrease
0.93(0.91–0.95)
P < 0.001
All-cause mortality, lower risk vs reference quartile: Q1 / Q2 / Q3
48, 55, and 67%; P < 0.05, for all
CV mortality, reduced risk vs lowest quartile: Q1 / Q2 / Q3
16, 49, and 77%; P < 0.05, for all

Further pooled results

Dose-response (restricted cubic splines)

Nonlinear dose-response association between step count and all-cause and CV mortality, progressively lower risk with increased step count
Pnonlineraly < 0.001, for both

Original publication

The association between daily step count and all-cause and cardiovascular mortality: a meta-analysis. Eur J Prev Cardiol. Published 9 August 2023. doi:10.1093/eurjpc/zwad229

Composed by AI from the published abstract and checked against it. How Briefs are made →

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