Heart failure & cardiomyopathies
The Diagnostic HCM (D-HCM) Score, a New Diagnostic Tool for Distinguishing Hypertrophic Cardiomyopathy from Hypertensive Cardiopathy
Authors' conclusion
The QRS duration in patient with HCM is significantly shorter compared with patients with HHD-related LVH. QRS duration can be used as a diagnosis marker to distinguish between HCM and HHD. The D-HCM score is a novel, simple, and accurate diagnosis tool for HCM patients with mild to moderate phenotypes.
Study context
- Population
- Patients with LVH due to hypertrophic cardiomyopathy (HCM) or hypertensive heart disease
- Participants
- 547 vs 139
- Comparison
- HCM vs hypertensive heart disease (HHD); D-HCM score for diagnosis of HCM
- HCMn = 547
- HHDn = 139reference
- Outcome
- QRS duration in HCM vs HHD
Methodological detailsretrospective, international, multicentre
- Retrospective
- International
- Multicentre
Performance
As reported in the abstract
QRS duration
P < 0.01
Further findings
| Outcome | Values |
|---|---|
| Diagnostic performance of D-HCM score for true HCM | QRS-HCM score ≥2 Sensitivity 79% · Specificity 99% · NPV 55% · PPV 99% |
Diagnostic performance of D-HCM score for true HCM
- D-HCM score: no antihypertensive drugs (+2); family history of unexplained sudden death (+2); QRS duration <95 ms (+1); maximum wall thickness ≥17 mm (+1)
Original publication
The D-HCM Score, a New Diagnostic Tool for Distinguishing Hypertrophic Cardiomyopathy from Hypertensive Cardiopathy. ESC Heart Fail. Published 23 July 2024. doi:10.
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