Arrhythmias & electrophysiology
The First Brazilian Cardiovascular Registry of Atrial Fibrillation: Primary Results of the RECALL Study
Authors' conclusion
RECALL represents the largest prospective registry of patients with AF in Latin America. Our findings highlight important gaps in treatment
Study context
- Population
- Patients with Atrial Fibrillation (AF) in Brazil, April 2012 to August 2019
- Participants
- 4,585 patients89 sites
- Outcome
- Characteristics, treatment patterns and clinical outcomes of patients with AF
- Follow-up
- 1 year
Methodological detailsmulticentre, nationwide, 89 sites, 1-year follow-up
- Multicentre
- Nationwide
- 89 sites
- 1-year follow-up
Main finding
As reported in the abstract
Clinical outcomes (rates/100 patient-years)
- Death, rate/100 patient-years
- 5.76 (5.12-6.47)
- Hospitalization due to AF, rate/100 patient-years
- 15.8 (14.6-17.0)
- AF ablation, rate/100 patient-years
- 5.0 (4.4-5.7)
- Cardioversion, rate/100 patient-years
- 1.8 (1.4-2.2)
- Stroke, rate/100 patient-years
- 2.77 (2.32-3.32)
- Systemic embolism, rate/100 patient-years
- 1.01 (0.75-1.36)
Observational data: associations, not effects.
Further findings
Baseline characteristics
- Median age (years)
- 70 (61, 78)
- Women
- 46%
- Permanent AF
- 53.8%
- Previous AF ablation
- 4.4%
- Previous cardioversion
- 25.2%
- Mean (SD) CHA2DS2-VASc score
- 3.2 (1.6)
- Median HAS-BLED score
- 2 (2, 3)
Anticoagulation at baseline
- Not on anticoagulants
- 22%
- VKA, among anticoagulated
- 62.6%
- DOAC, among anticoagulated
- 37.4%
- Reason for no OAC: physician judgment
- 24.6%
- Reason for no OAC: difficulty controlling INR
- 14.7%
- Reason for no OAC: difficulty performing INR
- 9.9%
Anticoagulation during follow-up
- Mean (SD) TTR for the study period
- 49.5% (27.5)
- Anticoagulant use
- 87.1%
- INR in therapeutic range
- 59.1%
Predictors of mortality (multivariable)
- Older age, permanent AF, NYHA class III/IV, CKD, PAD, stroke, COPD and dementia independently associated with increased mortality
- Anticoagulant use associated with lower risk of death
Safety
Major bleeding, rate/100 patient-years · 1 year
- Major bleeding
- 2.21 (1.81-2.70)
Original publication
The First Brazilian Cardiovascular Registry of Atrial Fibrillation: Primary Results of the RECALL Study. Am Heart J. Published 15 June 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →